Protein Modification Reagents

Medchemexpress LLC Azido-PEG4-azide | 182760-73-2 | ≥97.0% | 288.30 | 100 MG

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Azido-PEG4-azide | 182760-73-2 | ≥97.0% | 288.30 | 100 MG

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Medchemexpress LLC DSPE-PEG-endo-BCN | 92.1% | 5000 (Average) | 1 MG

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DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. It can be used in drug delivery research.

• Improves delivery efficiency of poorly soluble drugs
• Enhances tissue specificity
• Suitable for drug delivery research

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eMolecules​ TCO-PEG4-Val-Cit-PAB-PNP | Broadpharm |944.049 | C45H65N7O15 | 98.000 | CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)OC1CCC\C=C\CC1)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 25mg | 528284360

TCO-PEG4-Val-Cit-PAB-PNP | Broadpharm |944.049 | C45H65N7O15 | 98.000 | CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCNC(=O)OC1CCC\C=C\CC1)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc(cc2)[N+]([O-])=O)cc1 | 25mg | 528284360

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Medchemexpress LLC DBCO-PEG4-Biotin | 1255942-07-4 | 99.5% | 100 MG

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DBCO-PEG4-Biotin is an azadibenzocyclooctyne-biotin derivative that features a biotin group and four polyethylene glycol (PEG) units. This versatile biotinylation reagent is utilized for the introduction of a biotin moiety to azide-labeled biomolecules. It enables copper-free strain-promoted alkyne-azide click chemistry (SPAAC) reactions, leading to the formation of a stable triazole linkage.

• Contains a biotin group and four PEG units.
• Introduces a biotin moiety to azide-labeled biomolecules.
• Facilitates copper-free strain-promoted alkyne-azide click chemistry.
• Forms a stable triazole linkage.
• Utilized for research purposes.

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Medchemexpress LLC Dopamine-PEG-N3 MW 100mg

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Dopamine-PEG-N3 (MW 2000) (Dopamine-PEG-Azide (MW 2000)) is a compound composed of dopamine PEG segments and an azide group (-N3) Dopamine-PEG-N3 (MW 2000) can be used as a crosslinker to connect different materials together to build new composite materials and improve the performance of materials Dopamine-PEG-N3 (MW 2000) is a click chemistry reagent It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing an alkyne group

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eMolecules​ 1268135-96-1 | Benzyl-PEG2-amine | Broadpharm | MFCD20696222 | 195.262 | C11H17NO2 | 98.000 | NCCOCCOCc1ccccc1 | 500mg | 550804257

Benzyl-PEG2-amine | Broadpharm | 1268135-96-1 | MFCD20696222 | 195.262 | C11H17NO2 | 98.000 | NCCOCCOCc1ccccc1 | 500mg | 550804257

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eMolecules​ 2107273-00-5 | N-(azide-PEG3)-N'-(Ac-PEG3)-Cy7 | Broadpharm | MFCD29079412 | 792.420 | C43H58ClN5O7 | 97.000 | [Cl-].CC(=O)OCCOCCOCC[N+]1=C(\C=C\C=C\C=C\C=C2\N(CCOCCOCCOCCN=[N+]=[N-])c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 550804282

N-(azide-PEG3)-N'-(Ac-PEG3)-Cy7 | Broadpharm | 2107273-00-5 | MFCD29079412 | 792.420 | C43H58ClN5O7 | 97.000 | [Cl-].CC(=O)OCCOCCOCC[N+]1=C(\C=C\C=C\C=C\C=C2\N(CCOCCOCCOCCN=[N+]=[N-])c3ccccc3C2(C)C)C(C)(C)c2ccccc12 | 10mg | 550804282

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Medchemexpress LLC Amino-PEG4-CH2COOH | 195071-49-9 | MFCD27977508 | >=98.0% | 251.28 g/mol | C10H21NO6 | 1 G

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Amino-PEG4-CH2COOH is a PEG4-based heterobifunctional linker with a terminal amino group and a terminal carboxymethyl (CH2COOH) group used as a hydrophilic spacer and reactive handle for conjugation in small-molecule and antibody conjugate synthesis.

• 4-unit polyethylene glycol spacer provides hydrophilicity and flexibility
• Terminal amine and carboxylic acid functional groups enable orthogonal conjugation chemistry
• Non-cleavable linker suitable for stable conjugates
• Available in laboratory-scale pack sizes for research use
• Supplied with high purity (typically >=98.0%)

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eMolecules​ 1426164-53-5 | Bis-Mal-Lysine-PEG4-TFP ester | Broadpharm | MFCD28385461 | 843.783 | C37H45F4N5O13 | 98.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)C(CCCCNC(=O)CCN2C(=O)C=CC2=O)NC(=O)CCN2C(=O)C=CC2=O)c1F | 1g | 550804185

Bis-Mal-Lysine-PEG4-TFP ester | Broadpharm | 1426164-53-5 | MFCD28385461 | 843.783 | C37H45F4N5O13 | 98.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)C(CCCCNC(=O)CCN2C(=O)C=CC2=O)NC(=O)CCN2C(=O)C=CC2=O)c1F | 1g | 550804185

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eMolecules​ 1807540-84-6 | Mal-amido-PEG4-TFP ester | Broadpharm | MFCD28505515 | 564.487 | C24H28F4N2O9 | 95.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 5g | 550804212

Mal-amido-PEG4-TFP ester | Broadpharm | 1807540-84-6 | MFCD28505515 | 564.487 | C24H28F4N2O9 | 95.000 | Fc1cc(F)c(F)c(OC(=O)CCOCCOCCOCCOCCNC(=O)CCN2C(=O)C=CC2=O)c1F | 5g | 550804212

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Medchemexpress LLC Carboxy-PEG4-phosphonic acid | 1623791-69-4 | 96.0% | C11H23O9P | 100 MG

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Carboxy-PEG4-phosphonic acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are compounds with two distinct ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other the protein of interest. This mechanism allows PROTACs to leverage the intracellular ubiquitin-proteasome system for selective degradation of target proteins.

• PEG-based PROTAC linker
• Used in the synthesis of PROTACs
• Enables selective degradation of target proteins

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Cambridge Isotope Laboratories GLYCAN-O6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL

GLYCAN-O6-13C-GAL4 (GALACTOSE-13C6, 99%), 500 PMOL

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eMolecules​ N-(acid-PEG24)-N-bis(PEG3-azide) | Broadpharm |1548.818 | C67H133N7O32 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCN=[N+]=[N-] | 100mg | 563055202

N-(acid-PEG24)-N-bis(PEG3-azide) | Broadpharm |1548.818 | C67H133N7O32 | 98.000 | OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(CCOCCOCCOCCN=[N+]=[N-])CCOCCOCCOCCN=[N+]=[N-] | 100mg | 563055202

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eMolecules​ 1821017-46-2 | Methyltetrazine-Sulfo-NHS ester | Broadpharm | MFCD29052195 | 429.340 | C15H12N5NaO7S | 95.000 | [Na+].Cc1nnc(nn1)-c1ccc(CC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)cc1 | 10mg | 296213298

Methyltetrazine-Sulfo-NHS ester | Broadpharm | 1821017-46-2 | MFCD29052195 | 429.340 | C15H12N5NaO7S | 95.000 | [Na+].Cc1nnc(nn1)-c1ccc(CC(=O)ON2C(=O)CC(C2=O)S([O-])(=O)=O)cc1 | 10mg | 296213298

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Medchemexpress LLC Mal-PEG4-NHS ester | 1325208-25-0 | 99.4% | 442.42 | C19H26N2O10 | 5 G

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Mal-PEG4-NHS ester is a heterobifunctional polyethylene glycol (PEG) linker bearing a terminal maleimide and an N-hydroxysuccinimide (NHS) ester. It is used to conjugate sulfhydryl-containing molecules to primary amines for bioconjugation applications such as antibody-drug conjugates and linking quantum dots to PEGylated liposomes.

• heterobifunctional linker enabling thiol-to-amine conjugation
• contains a four-unit peg spacer to improve solubility and reduce steric hindrance
• maleimide group reacts selectively with sulfhydryl groups
• nhs ester reacts with primary amines under mild conditions
• provided as a high-purity reagent suitable for research use

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